Natural Product Screening using Ligand Fishing and Bioaffinity Chromatography

Ruin Moaddel, Baltimore, Baltimore, USA (rmoaddel@hotmail.com)

Natural product extracts can be considered an invaluable source of biologically active secondary metabolites. It has been demonstrated that the screening of natural products is a viable approach for the identification of bioactive compounds and can be a successful approach for the discovery of new drug leads. Ligand fishing and bioaffinity chromatography offers new opportunities for the rapid identification of active metabolites from complex matrixes. Examples of this approach will be discussed