Accelerating Drug Development, QC & Manufacturing
with new Technologies in Molecular Spectroscopy

Dr Jan Wülfken, Agilent Technologies, Germany

This talk will describe newest breakthrough technologies and applications of Raman, Laser based Infrared and UV-Vis Spectroscopy in Pharma. This will include use of Raman for raw materials verification of incoming goods through unopened non-transparent container materials to streamline the drug manufacturing process and the use of transmission Raman as an alternative to UPHPLC for content uniformity and polymorph studies. Furthermore, use of a next generation IR instrument using a quantum cascade laser will be described for chemical imaging studies including analysis of tablet component distribution, polymorph distribution, salt exchange and stability studies. New breakthrough technologies for ultra-fast and productive parallel temperature based kinetic studies, protein folding, DNA melting and other temperature related UV-Vis measurements will end this overview. 

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Abstract Reference & Short Personal Biography of Presenting Author

Dr. Jan Wuelfken was born in Hamburg Germany and has made his PhD in biochemistry about NMR spectroscopic studies of CD4 binding peptides to inhibit the HIV infection. He is now for several years for Agilent responsible as a molecular spectroscopy product specialist for the support of the Raman, FT-IR, Fluorescence and UV-Vis/NIR business in all counties in EMEAI, where Agilent is working and supporting via distributors.