Fluorescent Reporters for Biomedical Applications

Leonid Patsenker, Ariel University, Ariel, Israel (leonidpa@ariel.ac.il)

Fluorescent reporters are the dye molecules or molecular systems that provide fluorescence signal for detection. These fluorescent compounds and materials are widely used in biomedical and related applications such as clinical diagnostics, biological imaging, photodynamic therapy (PDT), pharmaceutical research, high-throughput screening, food control, and environmental pollution monitoring. These materials are represented by the non-covalent probes, covalent labels, classification (coding) dyes, photosensitizers, and fluorescent standards. The current presentation focuses on the resent achievements of our research team and challenging tasks in the field of the development of fluorescent reporters for biomedical applications. The emphasis is on the near-IR spectral rang, brightness, sensitivity, stability, long and environment sensitive fluorescence lifetimes.

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Abstract Reference & Short Personal Biography of Presenting Author

Dr. Leonid Patsenker is an Associate Professor at the Department of Chemistry at the Ariel University, Israel. He studied Chemistry at the Kharkov State University, USSR and received his Ph.D. in 1989 from this University. Between 1986 and 2016 he worked at the State Scientific Institute for Single Crystals of the National Academy of Sciences of Ukraine, where for 10 years held the position of the Head of the Department of Organic Luminophores and Dyes. His research interests include the development of fluorescent dyes for biomedical applications, sensitizers for photodynamic therapy (PDT), organic scintillators, materials for LEDs, laser dyes, and sunlight converters. More then 100 developed fluorescent products have been commercialized. He has been the PI of about 30 national and international projects supported by the USA, EU, Canadian and Ukrainian Governments and companies. He has published over 100 research and review papers, 2 book chapters, and has held 24 patents. Upon his immigration to Israel in 2016, he started to work in the Department of Chemical Sciences at the Ariel University. The current research focuses on the development of fluorescence based systems for targeted drug delivery monitoring. This work is supported by the Israeli Scientific Foundation.