Quality evaluation of wolfberry from different regions in China based on the structure, yield and antioxidant activity of polysaccharides

Ying Wang, Institute For Control Of Chinese Traditional Medicine And Ethnic, National Institutes For Food And Drug Control, Beijing, China (wayi_1986@hotmail.com)

L. barbarum (wolfberry) has been widely cultivated in China, particularly in northwest regions.However, the fruit size and taste of L.barbarum from different habitats are quite different.Traditionally, only the fruit of L.barbarum produced in Ningxia province is recorded as an authentic herb,although the detailed mechanism responsible for this remains obscure. Polysaccharides are considered major active ingredients in L.barbarum which is crucial for its quality evaluation. In this study, we assessed the yield, monosaccharide composition, molecular weight, and linkage type of L.barbarum polysaccharides (LBPs) collected from different regions of China. The antioxidant activities of LBPs were also determined as its quality indicator. Our results showed that the similarity values of monosaccharide composition and glycoside bond fingerprints were larger than 0.9,and the Mw of the two fractions (peaks 1–2) in LBPs were ranging from 1.36 × 10⁶ to 2.01 × 10⁶ (peak 1), and 6.85 × 10⁴ to 10.30 × 10⁴ (peak 2) which indicated that the structure of LBPs were similar. However, the yield of LBPs from Qinghai province (low atmospheric temperature, high altitude) was significantly lower (p < 0.05) than those collected from Xinjiang and Ningxia province,which suggested that the L.barbarum produced in Ningxia and Xinjiang maybe more suitable as materials for medicines and functional foods.Our data also partially explain why the L.barbarum produced in Ningxia is recorded as an authentic herb.Moreover, the analytical methods established in this study could be used for quality control of L. barbarum.

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Abstract Reference & Short Personal Biography of Presenting Author

Miss Ying Wang received her Master's degree in the pharmacetical analysis, China National institute for food and drug control in 2011. After graduation, she worked in Institute for Control of Chinese Traditional Medicine and Ethnic Medicine (ICCTMEM), National Institutes for Food and Drug Control (NIFDC) until now. Her research has been focused on quality and safety evaluation of traditional Chinese medicine.So far, she has published over 20 scientific publications.

Reference

[1] Liu W, Xu J, Zhu R, Zhu Y.Fingerprinting profile of polysaccharides from Lycium barbarum using multiplex approaches and chemometrics. Int J Biol Macromol 2015;78:230-237. 

[2] Wu D T, Lam S C, Cheong KL, Wei F. Simultaneous determination of molecular weights and contents of water-soluble polysaccharides and their fractions from Lycium barbarum collected in China. J Pharm Biomed Anal2016;129: 210-218.