Synthesis, Characterization and Biological Activities of New Azo Ligands and thier Metal Complexes 4:-[(e)-(1,5-Dimethyl-3-Oxo-2-Phenyl-2,3-Dhydro-1h-Pyrazole-4-yl)Diazenyl] Pentane-2,4-Dione and its CO(ii), FE(iii), NI(ii) and CU(ii) Complexes

Agbo Ndidiamaka Justina, Department of pure and I ndustrial Chemistry, University of Nigeria, Nsukka., University of Nigeria, Nsukka, Nsukka, Nigeria

Aminoantipyrine was diazotized and coupled with pentane-2,4-dione to derivatize 3-[(E)-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dhydro-1H-Pyrazole-4-yl)diazenyl] pentane-2,4-dione). The Co(II),Fe(III) and Cu(II) and Ni(II) complexes of Ligand were also synthesized. DOPDPD was characterized based on the UV, IR, ¹H and ¹³C NMR Spectroscopy, Elemental analysis and X-Ray crystallogragh. However, the structures of the complexes were determined on the basis of conductance studies, stoichiometric determination, IR and electronic spectra. The ligand was tridentate coordination through oxygen and nitrogen and formed complexes of octahideral geometry with all the metal ions with general formula  ML₂  .The Ligand  at 20mg/cm³ concentration showed no activity against all the micro organisms.  However, the Co(II) complex was very active against all the microorganisms up to concentration .0.625 mg/cm³ when compared to ampicillin.