Accelerating Drug Development, QC & Manufacturing with new Technologies in Molecular Spectroscopy.

Jan Wuelfken, Agilent Technologies, Waldbronn, Germany (jan.wuelfken@agilent.com)

This talk will describe newest breakthrough technologies and applications of UV-Vis, Infrared and Raman Spectroscopy in Pharma. This will include use of Raman for raw materials verification of incoming goods through unopened non-transparent Containers materials to streamline the drug manufacturing process and the use of transmission Raman as an alternative to UPHPLC for content uniformity studies. Furthermore, use of a next generation IR instrument using a quantum cascade laser will be described for chemical imaging studies including analysis of tablet component distribution, polymorph distribution, salt exchange and stability studies. New breakthrough technologies for ultra-fast and productive protein folding, DNA melting and other temperature related UV-Vis measurements will end this overview.

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Short Biography of Presenting Author

Dr. Jan Wülfken is product specialist for molecular spectroscopy for Agilent Technologies. This includes different instrumentation like Raman, FTIR, UV-Vis/NIR and Fluorescence spectroscopy.