Toshio Suda M.D. PhD
Professor, Cancer Science Institute, National University of Singapore, Director, International Research Center for Medical Sciences (IRCMS), Kumamoto University
Hematopoiesis in Steady State and Under Stress

Curriculum Vitae of Professor Toshio Suda                                                         
Name: Toshio Suda - M.D. PhD
 Title:  Professor, Cancer Science Institute, National University of Singapore
　　　　　　Director, International Research Center for Medical Sciences
          (IRCMS), Kumamoto University

E-mail: sudato@keio.jp
1982     Research Associate, Department of Medicine,
          Medical University of South　Carolina (Dr. Makio Ogawa's Lab)
1983       Assistant Professor, Division of Hematopoiesis, Institute of Hematology,
          Jichi Medical School
1991       Associate Professor, Division of Hematology, Department of Medicine,
      Jichi Medical School
1992      Professor, Department of Cell Differentiation, Institute of Molecular Embryology and Genetics, Kumamoto University School of Medicine
 2002-2015  Professor, Developmental Biology, The Sakaguchi Laboratory,  
                 School of Medicine, Keio University
2014 till present     Professor, Cancer Science Institute of Singapore,
         National University of Singapore
2014 till present  Director, International Research Center for Medical Sciences
               (IRCMS), Kumamoto University

Membership and Editorials:

•    American Society of Hematology (Blood, Editorial Board)
•    Journal of Experimental Medicine (Editorial Board)
•    International Society of Stem Cell Research (ISSCR)
•    Cell Stem Cell (Editorial Board
•    Stem Cells (Editorial Board)
•    International Society for Experimental Hematology, Past President　　　　
•    Japanese Society of Hematology (International Journal of Hematology, Past Editor
in Chief)

Scientific Awards

1.    1990    Baelz Prize  “Paired daughter cell”
2.    2004   Baelz Prize   “Stem cell niche”
3.    2012   JSH Award   “ Hematopoietic Stem Cells”           
4.    2013   The 7th Mystery of Life Award
         The Seoul Archdiocesan Committee for Life
5.    2014      Metcalf Award “International Society of Experimental Hematology”

Research Biograph

HSCs give rise to stem cells (self-renewal) and to progenitor cells (differentiation). This fates decision is determined both by cell autonomous programs and by the surrounding microenvironment, or niche. His past work encompasses the study of the intrinsic and extrinsic regulation of HSCs (paired daughter cell experiments), purification of potent HSCs, analyses of cell differentiation processes, identification of cytokine signaling in hematopoiesis, and the characterization of HSC niches. He subsequently established the new field of oxidative stress and stem cell aging. He is clarifying the interaction of stem cells and niche. He will seek to establish a world-class research program of stem cell medicine　in NUS, which will show synergy with cancer sciences. Niche treatment includes manipulation of normal and cancer stem cells and ex vivo stem cell expansion, which will contribute to stem cell transplantation and cancer treatment.