Day 2 – April 6 2016

08:00-09:30
Registration
09:30-10:10
Plenary Session

Michael May

CCRM: Regenerative Medicine Commercialization Through Global Collaboration
Michael May, PhD

Centre for Commercialization of Regenerative Medicine, Canada
canada
10:10-10:40 coffee  Coffee Break and Poster Session
10:40 -12:20 Hall A Hall B Hall C Hall D
Stem cells in Tissue Engineering Pluripotent Stem Cells in Disease Regulation, Quality and Clinical Development Stem Cell Applications in Metabolic Diseases
Chair: Smadar Cohen Chair: Nissim Benvenisty Chair: Sigalit Ariely-Portnoy Chair: Yuval Dor
10:40 -11:00 Stem Cells in Tissue Engineering
Smadar Cohen
Ben-Gurion University, Israel
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Haploid Human Embryonic Stem Cells
Nissim Benvenisty
The Hebrew University, Israel
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Cell Therapy Submissions in Europe: Successes and Failures
Marcos Timon
AEMPS, Spain
spain
Cell Therapy for Diabetes: Human Embryonic Stem-Cells Derived Functional Insulin Producing Cells
Kfir Molakandon
Kadimastem Ltd., Israel
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11:00 -11:20 Regulation of Cardiomyocyte Differentiation and Dedifferentiation Induced by Varying Matrix Rigidity
Benny Geiger
Weizmann Institute of Science, Israel
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The Origin, Fate & Regulation of Stem Cells of the Corneal Epithelium: Lessons from iPS Cells and Lineage Tracing
Ruby Shalom
Technion, Israel
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Cell Therapy Products: Israeli MOH - Regulatory Update
Ofra Axelrod
MOH, Israel
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Beta-Cell Replication: the Role of the Pancreatic Microenvironment
Limor Landman
Tel Aviv University, Israel
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11:20 -11:40 The Matrix Reloaded: Engineering Functioning Tissue using Nature’s Building Blocks
Marcelle Machluf
Technion, Israel
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Using Patient-Specific Fibroblasts and iPSC-Derived Cardiomyocytes to Probe Monogenic Heart Diseases
Rivka Ofir
Ben Gurion University of the Negev, Israel
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Conclusions from Case studies: 10 Points to Consider when Developing a Cell Therapy Product
Diana Gershtein
GSAP, Israel
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Industrialization of a Cell Based Autologous Therapy Targeting Diabetes: Industrialization of Liver Cell Amplification Process from Culture Dish to Xpansion™ Multi-Plate Bioreactor
Sara Ferber
Orgenesis, Israel
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11:40 -12:00 Microgel Suspension Culture System for hMSCs Bioprocessing
Dror Seliktar
Technion, Israel
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Differential Methylation of the GGGGCC Repeat Expansion between C9/ALS HESCs and Patient-Derived iPS Cells
Rachel Eiges
The Hebrew University of Jerusalem, Israel
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The “Yellow Brick Road” to Methods Validation for Human Cell Therapy Products
Ruth Goldberg
Pluristem, Israel
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Development of an Endocrine Micro-Pancreas
Eduardo Mitrani
The Hebrew University of Jerusalem, Israel
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12:00 -12:20 Cardiac Tissue Engineering: from Development of Engineered Autologous Tissues to the Fabrication of Bionic Hearts
Sharon Fleischer
Tel Aviv University, Israel
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Latent Infection and Reactivation of the Human-Specific Pathogenic Virus Varicella Zoster using hESC-Derived Neurons- an in-Vitro Model for Herpes Zoster (Shingles)
Ron Goldstein
Bar-Ilan University, Israel
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Risk Based Thinking in Shipping Logistics
Ilana Avhar
World Courier, Israel
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The βAir Immune Barrier, A Potent Machinery for Protecting Xenogeneic Islets and Stem-Cell Based β-cells from Host Immune Systemβ-cells from Host Immune System
Uriel Barkai
ßeta-O2 Technologies Ltd. Israel
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12:30 -13:30 lunch  Lunch break
Hall A Hall B Hall C Hall D
  Programming of Adult Tissues Epigenetics of Stem Cells Combination Products:
Cells, Genes and Devices
In collaboration with

Biology and Translation of Cell Technologies
13:30 -15:10
Chair: Sara Ferber Chair: Yehudit Bergman Chair:
Yael Porat, Ohad Karnieli
Chair: Yaron Fuchs
13:30 -13:50 Generating Insulin Producing Cells by Transcription Factor-Induced Lliver Cell Transdifferentiation
Sara Ferber
Orgenesis / Sheba Medical Center, Israel
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Epigenetic Programming of Stem Cell Fate Decisions
Yehudit Bergman
The Hebrew University of Jerusalem, Israel
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Bringing Cell Therapies to Every Clinic - Vision and Practical Means
Yael Porat (10min)
BioGenCell Ltd, Israel
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Devises as a Tool to Standardize Cell and Gene Therapy - New Means to Make Cell Therapy Widely Available
Ohad Karnieli (10 min)
Karnieli Ltd, Israel
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Next Generation Cell Therapy Manufacturing
Eytan Abraham (15 min)
Lonza, USA


Engineering of Vascularized Flap Using Human Adipose Derived Endothelial Cells and Mesenchymal Stem Cells
Yulia Shandalov (15 min)
Technion, Israel
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Laser Stimulated Stem Cells in the Bone Marrow has Beneficial Effect on the Ischemic Heart and Kidney–a Bench to Bedside Study
Uri Oron (15 min)
Tel Aviv University, Israel
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Challenges in Developing Serum-Free Xeno-Free Differentiation Media for hMSC from Various Sources Toward Cell Therapy
Mira Genser-Nir (15 min)
Biological Industries, Israel
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Israeli Activity in the International ISO TC276 Standards for Biotechnology
Sagi Nahum (15 min)
Pluristem, Israel
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SEPT4/ARTS Regulates Stem Cell Apoptosis and Skin Regenration
Yaron Fuchs
Technion, Israel
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13:50 -14:10 Stem Cells are Key Players in Novel Skeletal Therapies
Dan Gazit
The Hebrew University of Jerusalem, Israel
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Epitranscriptomics - the Roles of mRNA Modification in Early Embryonic Cell Fate Decisions
Sharon Moshkovitz
Sheba Medical Center, Israel
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Metabolic Shifts in the Developing Tissue: A Potential Non-Genetic Means for Regulation of Cell Specification
Arieh Moussaieff
The Hebrew University of Jerusalem, Israel
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14:10 -14:30 Programming the Adult Human Kidney
Benny Dekel
Sheba Medical Center, Israel
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Chromatin Plasticity in Early Embryonic Stem Cell Differentiation: Imaging and in Silico Approaches
Eran Meshorer
The Hebrew University of Jerusalem, Israel
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Higher Genomic Stability of Mesenchymal Stem Cells Cultured for Regenerative Purposes: Lessons From the Tissue Specific Nature of Cells Isolated from Different Adult Sources
Nir Shani
Tel Aviv Sourasky Medical Center, Israel
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14:30 -14:50 The Fragile Identity of Pancreatic Beta Cells
Yuval Dor
The Hebrew University of Jerusalem, Israel
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Epigenetic Predisposition to Reprogramming Fates
Iftach Nachman
Tel Aviv University, Israel
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Computer-Based Assessment of Embryo Quality for Infertility Clinical Applications
Amnon Buxboim
The Hebrew University of Jerusalem, Israel
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14:50 -15:10 MicroRNAs Regulate Beta Cell Identity and Function
Eran Hornstein
Weizmann Institute of Science, Israel
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Large Scale Analysis of Loss of Imprinting in Human Pluripotent Stem Cells
Shiran Bar
Hebrew University, Jerusalem, Israel
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Mechanism of Action Placental-Derived Cellular Therapy for the Treatment of Peripheral Artery Disease
Racheli Ofir
Pluristem, Israel
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15:10 -15:40 coffee  Coffee Break
15:40 -16:20
Plenary Session
mendez-ferrer headshot Blood Stem Cells in Space and Time
Dr Simón Méndez-Ferrer

Department of Haematology, University of Cambridge, UK
UK
16:20 -16:30 GoldMedalAnnouncement of Winning Posters
Closing Remarks
Day1 Day2 Poster Session