Day 1 - 10 June 2014

8:00 - 9:15	Registration
9:15 - 9:30	Opening Dr. Avi Treves Sheba Medical Center, Chairman, Israstem 2014, Israel
09:30 - 10:10 Plenary Session: Chair: Prof. Joseph Itskovitz-Eldor	Stem Cell Genomics and Therapy for Neurodegenerative Disease Prof. Jeanne Loring Dept. of Chemical Physiology, Center for Regenerative Medicine, The Scripps Research Institute, California, USA
10:10 - 10:40	Coffee Break
	Hall A - Rayman Central	Hall B - Rayman West	Hall C - Rayman East
10:40 - 12:40	Session A: New Technologies and Tools in Translation Chair: Prof. Joseph Itskovitz-Eldor	Session B: Regenerative Cardiovascular Medicine Chair: Prof. Jonathan Leor	Session C: Cell Therapy in Tissue Engineering and Connective Tissues Chair: Prof. Shulamit Levenberg
10:40 - 11:00 Keynote Lectures	Building Bridges from Research to Therapy: a Roadmap for the Successful Generation of Clinical-Grade IPSCs Dr. Thomas Fellner CDO, Lonza, Inc, Walkersville, USA	Heart Development and Regeneration: Fixing a Broken Heart Prof. Eldad Tzahor Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel	Biomaterials Regulate Stem Cell Fate Prof. Smadar Cohen Biotechnology Engineering, Ben-Gurion University, Beer Sheva, Israel
11:00 - 11:20	Scaling-Up Stem Cell Manufacturing Jose Castillo Cell Culture Technologies, Pall LifeSciences, Brussels, Belgium	VEGF: More Than Just an Angiogenic Factor Prof. Eli Keshet Developmental Biology and Cancer Research, The Hebrew University-Hadassah Medical Center, Jerusalem, Israel	Translation of Stem Cell Therapies for Skeletal Disorders Prof. Dan Gazit Faculty of Dental Medicine, The Hebrew University–Hadassah, Jerusalem, Israel
11:20 - 11:40	Integrated Research Tools for Stem Cells Differentiation and Characterization Ella Buzhor Biology, LifeMap Sciences, Tel Aviv, Israel	Cell and Gene Therapy Strategies for Myocardial Repair Prof. Lior Gepstein Rappaort Faculty of Medicine and Research Institute, Technion, Haifa, Israel	Engineering Vascularized Tissue for Muscle Regeneration Dr. Yulia Shandalov Biomedical Engineering, Technion, Haifa, Israel
11:40 - 12:00	‘Next-Generation’ Biobanking for Health Innovation Dr. Assaf Bahat Kalia Biotech, Kibbutz Kalia, Israel	The Dark Side of the Force: Mesenchymal Stromal/Stem Cells in Heart Repair Prof. Jonathan Leor Cardiovascular Research Institute and Regenerative Medicine Center, Tel-Aviv University and Sheba Medical Center, Israel	Tuning the Ratio of Synthetic to Natural Components in a Biosynthetic Hydrogel for Optimal MSC Chondrogenic Differentiation Dr. Roni Wechsler Regentis Biomaterials, Or Akiva, Israel
12:00 - 12:20	A Novel Xeno-Free Culture System for the Isolation and Expansion of hMSC from Various Sources for Cell Therapy Applications Dr. Mira Genser-Nir Biological Industries, Beit-Haemek, Israel	Use of Genetically Engineered Cells for Vascularization: Convergence of Cell and Gene Therapies Prof. Moshe Flugelman Lady Davis Carmel Medical Center, Haifa, Israel	Stem Cells Feel into their Surroundings by Nuclear Mechanosensitivity Dr. Amnon Buxboim Life Sciences & Bioengineering, The Hebrew University of Jerusalem, Israel
12:20 - 12:40	Safety and Efficacy of Placental eXpanded (PLX-PAD) Cells in the Treatment of Muscle Injury Dr. Esther Lukasiewicz Hagai Clinical and Medical Affairs, Pluristem Therapeutics, Haifa, Israel	Stem Cell Transplantation Reverses Ischemic Mitral Regurgitation (IMR) Prof. Arnon Blum Department of Internal Medicine, The Baruch Padeh Medical Center, Poriya, Israel	Use of Immature Dental Pulp Stem Cells for Maxillary Sinus Bone Restoration. Clinical Cases Report Camila Favero de Oliveira Genetic, Butantan Institute, Ribeirão Preto / SP, São Paulo, Brazil
12:30 - 14:00	Lunch Break
14:00 - 14:40 Plenary Session: Chair: Prof. Ella Naparstek	Innovating Preclinical Drug Discovery & Human Cell Therapy Dr. Stephen Minger Global Head of Research and Development for Cell Technologies, GE Healthcare Life Sciences, UK
14:40 - 15:10	Coffee Break

	Hall A - Rayman Central	Hall B - Rayman West
15:10 - 16:50	Session D: Quality, Regulatory, Bioassays and Manufacturing Challenges Chair: Dr. Sigalit Ariely-Portnoy Co chair: Dr. Ofra Axelrod	Session E: Hematological Diseases and Immunotherapy Chair: Prof. Ella Naparstek
15:10 - 15:30 Keynote Lectures	Current Regulatory Topics in Europe Dr. Ilona Reischl AGES/BASG, Vienna, Austria	Apoptotic Cell Therapy for the Treatment of GvHD and Autoimmunity Prof. Dror Mevorach Internal Medicine Department, Hadassah Medical Center, Jerusalem, Israel
15:30 - 15:50	ISCT 2014 Annual Meeting Report: Trends in Developments, Regulatory and Operations in Cell Therapy Dr. Sigalit Ariely-Portnoy Gsap, Shave-Zion, Israel	MSCs for GVHD: How does it Work? When does it work? Does it Work at All? Analysis of an Experience Prof. Igor B. Resnick Bone Marrow Transplantation, Hadassah-HUJI Medical Center, Jerusalem, Israel
15:50 - 16:10	Cellection of Stem Cells - Moving from biomarkers to Function: an Innovative Regulatory Pathway Shai Yarkoni Cellect biotechnology, Kfar Saba, Israel	NiCord®, Umbilical Cord Blood Expanded ex vivo with Nicotinamide, Provides Early and Long-term Multi-lineage Engraftment in Patients with Hematological Malignancies Hadas Shoham Nissan Gamida Cell, Jerusalem, Israel
16:10 - 16:30	Transferring Cell Therapy from the Bench to the Industry: Quality, Cost and Manufacturing Efficiency Dr. Ohad Karnieli Technology, Pluristem Therapeutics, Haifa, Israel	Immunotherapy of Hematologic Malignancies by Autologous and Allogeneic Cell Therapy; Past Accomplishment and Future Goals Prof. Shimon Slavin The International Center for Cell Therapy & Cancer Immunotherapy (CTCI) Tel Aviv, Israel
16:30 – 16:50	Comparability Study: Managing Process Changes Dr. Sigalit Ariely-Portnoy Gsap, Shave-Zion, Israel	Blockade of PD-1 in Conjunction With Dendritic Cell/Myeloma Vaccines Following SCT Dr. Tami Katz Stem cell Transplantation Laboratory, Department of Hematology and Bone Marrow Transplantation Rambam Health Care Campus, Haifa, Israel

This program is subject to change